2H-1-Benzopyran-2-one, 7-[[4-amino-6-[(2-methylphenyl)amino]-1,3,5-triazin-2-yl]methoxy]-4-methyl-
GPR40/FFAR1 modulator 1
CAS: 874755-26-7
Molecular Formula: C21H19N5O3
2H-1-Benzopyran-2-one, 7-[[4-amino-6-[(2-methylphenyl)amino]-1,3,5-triazin-2-yl]methoxy]-4-methyl- - Names and Identifiers
| Name | GPR40/FFAR1 modulator 1 |
| Synonyms | 2H-1-Benzopyran-2-one, 7-[[4-amino-6-[(2-methylphenyl)amino]-1,3,5-triazin-2-yl]methoxy]-4-methyl- |
| CAS | 874755-26-7 |
2H-1-Benzopyran-2-one, 7-[[4-amino-6-[(2-methylphenyl)amino]-1,3,5-triazin-2-yl]methoxy]-4-methyl- - Physico-chemical Properties
| Molecular Formula | C21H19N5O3 |
| Molar Mass | 389.41 |
| Density | 1.370±0.06 g/cm3(Predicted) |
| Boling Point | 690.2±65.0 °C(Predicted) |
| Solubility | DMSO : 15 mg/mL |
| pKa | 3.52±0.10(Predicted) |
| Storage Condition | -20℃ |
| Use | GPR40/FFAR1 modulator 1 is an agonist of Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1) and its allosteric modulator. |
| Target | Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1) |
2H-1-Benzopyran-2-one, 7-[[4-amino-6-[(2-methylphenyl)amino]-1,3,5-triazin-2-yl]methoxy]-4-methyl- - Reference
| Reference Show more | 1. Lückmann M, et al. Molecular dynamics-guided discovery of an ago-allosteric modulator for GPR40/FFAR1. Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):7123-7128. |
2H-1-Benzopyran-2-one, 7-[[4-amino-6-[(2-methylphenyl)amino]-1,3,5-triazin-2-yl]methoxy]-4-methyl- - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.568 ml | 12.84 ml | 25.68 ml |
| 5 mM | 0.514 ml | 2.568 ml | 5.136 ml |
| 10 mM | 0.257 ml | 1.284 ml | 2.568 ml |
| 5 mM | 0.051 ml | 0.257 ml | 0.514 ml |
Last Update：2024-01-02 23:10:35
![2H-1-Benzopyran-2-one, 7-[[4-amino-6-[(2-methylphenyl)amino]-1,3,5-triazin-2-yl]methoxy]-4-methyl-](http://res.chembk.com/assets/images/structure/5400500.gif)
Supplier List
View History